Faculty

Changkun LITenured Associate Professor

Tel: 021-54738144 
Email: chkli@sjtu.edu.cn 
Address: 上海市东川路800号太阳成集团tyc7111ccB楼237  
Home Page: https://www.x-mol.com/groups/Li-Changkun?lang=zh 

Educational Background

2000-2004       B.S. Chemistry, Peking University, P. R. China.
2004-2010       Ph.D. Organic Chemistry, Peking University, P. R. China.
                           with Prof. Jianbo Wang and Yan Zhang


Work Experience

2016.03-now         Associate Professor, group leader
                              School of Chemistry and Chemical Engineering                     
                              Shanghai Jiaotong University, P. R. China

2012.10-2016.02   PostDoc, Humboldt Fellow
                              Institut für Organische Chemie,
                              Albert-Ludwigs-Universität Freiburg, Germany
                              Supervisor: Professor Bernhard Breit

2010.07-2012.10   PostDoc, JSPS Fellow
                              Department of Synthetic Chemistry and Biological  
                              Chemistry, Graduate School of Engineering,
                              Kyoto University, Japan
                              Supervisor: Professor Masahiro Murakami


Research Interests

Organometalic Chemistry, Asymmetric Catalysis and Organic Synthesis

Publications

  (17) Rh-Catalyzed Regio- and Enantioselective Allylic Phosphinylation

Bing Li, Min Liu, Sajid Ur Rehman, and Changkun Li*

J. Am. Chem. Soc. 2022144,  2893-2898.


(16)  Eantioselective Synthesis of Pyridiens with All-Carbon Quaternary Carbon Centers via Cobalt-Catalyzed Desymmetric

[2+2+2] Cycloaddition

Ke Li, Linsheng Wei, Minghe Sun, Bing Li, Min Liu, Changkun Li* 

Angew. Chem. Int. Ed. 202160, 20204-20209.


(15)  Rhodium-Catalyzed Regio- and Enantioselective Allylic Amination of racemic 1,2-Disubstituted Allylic Phosphates.

Wen-Bin Xu,† Minghe Sun,† Mouhai Shu, Changkun Li* (†, equal contribution)

J. Am. Chem. Soc. 2021143, 8255-8260.


(14)  Rh-Catalyzed Chemodivergent Regio- and Enantioselective Allylic Alkylation of Indoles
Minghe Sun, Min Liu, Changkun Li*

Chem. Eur. J. 202127, 3457-3462.

 


(13) Enantioselective Synthesis of 3-Allylindolizines via Sequential Rh-Catalyzed Asymmetric Allylation and Tschitschibabin Reaction
Ke Li, Changkun Li*

Org. Lett. 202022, 9456-9461.


(12) Regio- and Enantioselective Allylic Alkylation of Terminal Alkynes by Synergistic Rh/Cu Catalysis

Wen-Yu Huang, Chun-Hua Lu, Samir Ghorai, Bing Li, Changkun Li*

J. Am. Chem. Soc. 2020142, 15276-15281. 

 


(11) Desymmetrization construction of chiral lactones by synergistic Cu(II) complex and organic base

Murad Ali, Changkun Li*

Tetrahedron Lett. 2020, https://doi.org/10.1016/j.tetlet.2020.152106


(10) Cobalt/Bisoxazolinephosphine-Catalyzed Asymmetric Alkynylation of Isatins

Jia-Feng Chen, Changkun Li*

Org. Lett. 202022, 4686–4691

 


(9) Rh(I)-Catalyzed Regio- and Enantioselective Allylic Alkylation of Meldrum's Acid 

Min Liu, Haiying Zhao,* Changkun Li.*

Chin. Chem. Lett. 202132, 385-388.

 


(8) Cobalt-Catalyzed Regio- and Enantioselective Allylic Alkylation of Malononitriles

Samir Ghorai, Sajid Ur Rehman, Wen-Bin Xu, Wen-Yu Huang, Changkun Li.*

Org. Lett. 202022, 3519-3523.


(7) Rh(I)/Bisoxazolinephosphine-Catalyzed Regio- and Enantioselective Allylic Substitutions

Wen-Bin Xu, Samir Ghorai, Wenyu Huang, Changkun Li.*

ACS. Catal202010, 4491-4496. 

 


(6)  Pd-Catalyzed Enantioselective Synthesis of 2-Methyl-3-methyleneindoline. 

Chun-Hua Lu, Sima, Darvishi, Vahid, Khakyzadeh, Changkun Li.*

Chin. Chem. Lett. 202031, doi.org/10.1016/j.cclet.2020.02.056. 


(5) Cobalt-Catalyzed gem-Cross-Dimerization of Terminal Alkynes.

Jia-Feng Chen, Changkun Li.*

ACS. Catal. 202010, 3881-3889. 

 



(4) Cobalt-Catalyzed Regio- and Enantioselective Allylic Amination.

Samir Ghorai, Sahadev Shrihari Chirke, Wen-Bin Xu, Jia-Feng Chen, Changkun Li.*

J. Am. Chem. Soc. 2019141, 11430−11434.


(3) Construction of Vicinal Quaternary Carbon Centers via Cobalt-Catalyzed  Asymmetric Reverse Prenylation.

Minghe Sun#, Jia-Feng Chen#, Shufeng Chen, Changkun Li.*

Org. Lett. 201921, 1278-1281. (#, equal contribution)

 


(2) Enol Ester Synthesis via Cobalt-Catalyzed Regio- and Stereoselective

Addition of Carboxylic Acids to Alkynes.

Jia-Feng Chen, Changkun Li.*

Org. Lett. 2018, 20, 6719-6724.


(1)  Rh(I)-Catalyzed Carbonylative [3+1] Constrcution of Cyclobutenones

via C-C s-Bond Activation of Cyclopropenes.

Wen-Bin Xu, Changkun Li,* and Jianbo Wang

Chem. Eur. J. 2018, 24, 15786-15790. 



Honors and Awards

2020 Thieme Chemistry Journal Award

2013 Humboldt Fellowship

2011 JSPS Fellowship


Address:800 Dongchuan RD. Minhang District, Shanghai, China
PostCode:200240 Tel:021-54742893 E-mail:sjtuscce@sjtu.edu.cn

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